IgG4 associated autoimmune hepatitis: a differential diagnosis for classical autoimmune hepatitis
نویسندگان
چکیده
منابع مشابه
Autoimmune hepatitis
Autoimmune hepatitis is (AIH) is a chronic hepatitis that occurs in children and adults of all ages. It is characterized by immunologic and autoimmune features, including circulating auto antibodies and high serum globulin concentrations. It was first described in the 1950s by term of chronic active hepatitis. It has 2 types with different auto antibodies. Diagnosis is based upon serologic and ...
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Background: Autoimmune hepatitis (AIH) in childhood has variable modes of presentation, and the disease should be suspected and excluded in all children presenting with symptoms and signs of prolonged or severe acute liver disease. In AIH, the liver biopsy histopathology shows inflammation in addition to presence of serum autoimmune antibodies and increased levels of immunoglobulin G (IgG). Ob...
متن کاملAutoimmune hepatitis.
N Engl J Med 2006;354:54-66. Copyright © 2006 Massachusetts Medical Society. A utoimmune hepatitis is a generally progressive, chronic hepatitis of unknown cause that occurs in children and adults of all ages. Occasionally, it has a fluctuating course, with periods of increased or decreased activity. The diagnosis is based on histologic abnormalities, characteristic clinical and biochemical fin...
متن کاملAutoimmune hepatitis.
Autoimmune hepatitis is an uncommon disease causing chronic inflammation of the liver and associated with various circulating autoantibodies. It shares some characteristics with other autoimmune liver diseases, such as primary biliary cirrhosis and sclerosing cholangitis. There has been confusion in past years regarding this entity, but there are now recognized diagnostic criteria by which to m...
متن کاملAutoimmune hepatitis.
Autoimmune hepatitis (AIH) is a rare disease, characterized by female predominance, hypergammaglobulinemia, autoantibodies, association with HLA DR3 and HLA DR4 and a good response to immunosuppression. Different subtypes of AIH may be distinguished, based on differences in the autoantibody patterns. AIH type 1 is characterized by anti-nuclear (ANA) and/or anti-smooth muscular (SMA) autoantibod...
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ژورنال
عنوان ژورنال: Gut
سال: 2007
ISSN: 0017-5749
DOI: 10.1136/gut.2007.122283